Alcoholic extract of Curcuma longa L. (Haldi) was evaluated for its antipyretic activity on Escherichia coli induced pyrexia in albino rats. The alcoholic extract of Curcuma longa was administered (600 mg/kg body weight, intraperitoneally), one hour after administration of E. coli organism. The change in temperature was from 37.11°C to 37.28, 37.4 and 38.15°C at first, second and third hour of administration of Curcuma longa, respectively. The changes were significant at second and third hours of administration, however at first hour the change was non significant as compared to control. The C. longa was found to be less potent than standard antipyretic drug Paracetamol (100 mg/kg b.w., I/P).
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